Publication: BBB Lab

The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review

Till, M. A. C., H. M. O. Reid, I. Murphy, and B. R. Christie. 2026.

“The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review.” Hippocampus 36, no. 5: e70121.

https://doi.org/10.1002/hipo.70121.

This systematic review highlights how the movement of specialized brain cells—called interneurons—into the hippocampus plays a crucial role in healthy brain development. The authors bring together emerging evidence showing that when this migration process is disrupted, it can alter how hippocampal circuits form and function, contributing to neurodevelopmental conditions such as autism and schizophrenia. By clarifying these cellular pathways, the study helps point toward new directions for understanding, detecting, and potentially intervening in disorders linked to early‑life changes in brain wiring.

Mia Till completed her BSc Honours Thesis in the Blood-Brain Barrier Lab in 2026, under the supervision of Dr. Alon Friedman. She is currently a Masters student at UVic, continuing her research into TBI, under the supervision of Dr Brian Christie.